PRODUCTS

 We offer optimized protocol-ready high throughput screening solutions
for a range of pre- and post-clinical applications in neuroscience, oncology and infectious diseases.


NeuroHTS™


 
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  • The first-in-class high-throughput in vitro platform for neuronal network formation and screening
  • 3000 neurons and 120 single axon replicates per sample
  • Generate high-quality, reproducible results faster
  • Compatible with industrial automation solutions such as liquid handlers and plate imagers
  • Improve standardization, efficiency, reproducibility, and reliability
  • Reduce and replace animal experiments with more human-relevant models

Compatible with various cell and spheroid types from both human and animal origin.

NeuroHTS™ gives you perspective on the clinical viability of your therapeutic candidates by facilitating growth of a cell culture microenvironment that is more representative of a clinical context.


What you can do with NeuroHTS™

Pre-clinical assays:

  • Viral transport and MoA analyses
  • Drug screening assays
  • Neurotoxicity assays

Human disease modelling:

  • Parkinson’s Disease
  • Spinal cord injury
  • Multiple sclerosis
  • Alzheimer’s Disease
  • ALS

Clinical/translational assays with personalized neuronal response analyses


Additional Applications

  • Receptor ligand interaction
  • Synapse formation
  • Network formation
  • Microglia formation
  • Neuronal cell-to-cell communication with other cell types (e.g. microglia, astrocytes, etc.)
  • Virus transport in neurons (e.g. Herpes virus, rabies virus, etc.)
  • Axonal growth
  • Axonal degeneration and regeneration
  • Axonal transport

High throughput, automation compatible, scalable imaging and biochemistry analyses with no additional equipment needed

Step 1 - Grow and differentiate neuronal cells using NeuroHTS™, and conduct experiments
Step 2 - Collect results using standard plate reader and microscope
Step 3 - Analyze results

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Our high throughput products offer:

Improved Clinical Relevance
Neuronal networks organization that is similar to human physiology

Standardization
All neuronal networks are grown, tested, and analyzed under standardized conditions

Reproducibility
Parallel axon organization pattern for easy comparison within the same test and between tests

Ease of Analysis
Clear neuronal organization lower barrier for complex neuronal network analysis

Lower Costs
Requires fewer cells, less reagents, fewer animals, and less time

NeuroHTS™ is an ANANDA trademark.